Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc13.5 | The curious case of growth hormone | ECE2018

Growth hormone acts in AgRP neurons to control energy expenditure during food restriction and promotes counter-regulatory responses to hypoglycemia via the ventromedial hypothalamus

Furigo Isadora C , Teixeira Pryscila DS , Souza Gabriel O , List Eduard , Kopchick John , Donato Jose

Growth hormone (GH) responsive cells are extensively distributed in central nervous system, including in neurons of the arcuate (ARH) and ventromedial nucleus (VMH) of hypothalamus, areas that control food intake, energy expenditure and blood glucose. During metabolic stresses, such as food restriction and hypoglycemia, GH secretion is stimulated and may be important to maintain survival. In the present study, we first verified that an acute GH injection stimulates food intake...